Breast cancer remains a major health problem worldwide.While chemotherapy represents an important therapeutic modality against breast cancer, limitations in the clinical use of chemotherapy remain formidable because of chemoresistance.The HER2/PI-3K/Akt pathway has been demonstrated to play a causal role in conferring a broad chemoresistance in bre

This study integrated Larder Fridge investigates dynamic behaviors of hypoid gear rotor systems under variable tidal current energy harvesting conditions through numerical simulations and experimental validation.The study examines dynamic responses of a hypoid gear rotor system induced by cyclical tidal current variations, which generate fluctuatin

Since a racemic mixture of chiral nucleotides frustrates the enzymeless extension of RNA and DNA, the origin of homochirality must be intimately connected with the origin of life.Homochirality theories have elected to presume abiotic mechanisms for prebiotic enantiomer enrichment and post amplification, but none, so far, has been generally accepted